Design and Optimization in organic synthesis(elsevier经典)

fenglianxiang

Data Handling in Science and Technology---Vol 24
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Design and Optimization in Organic Synthesis
By Rolf Carlson and Johan Carlson

9 z9 N2 Q, e' H8 P5 \/ yContents
Chapter 1   Introduction: Strategies on different levels in organic synthesis.
Chapter 2   Experimental study of reaction conditions. Initial remarks.
, y; C$ F1 s  a+ w. }  w4 AChapter 3   Models as tools.
1 _9 \( M  u5 d0 Q2 MChapter 4   General outline of screening experiments.
9 X4 `6 A* [6 nChapter 5   Two-level factorial designs.
Chapter 6   Two-level fractional factorial designs.
Chapter 7   Other designs for screening experiments.
1 C( X6 t, Q8 u( `+ o) lChapter 8   Summary of screening experiments.
Chapter 9   Optimisation.
  e" @; }+ y0 T+ rChapter 10  Steepest ascent.
. {0 p8 L+ B7 q& ~" `Chapter 11  Simplex methods.
5 Z% i" G/ H) w( A) s9 Q- I. wChapter 12  Response surface methods.
- O) |4 b2 n5 J- ^7 OChapter 13  Reaction kinetics by sequential response surface modelling.
1 g# ~4 w1 ]7 `+ YChapter 14  Summary of strategies for exploring the experimental space.
) [* Q: X8 e) d- ~, X* hChapter 15  The reaction space.
* {$ b' |! S: N8 F" z0 P* qChapter 16  Principal properties.
! Y2 M& ?4 X' r9 r- K# u2 I) WChapter 17  Strategies for the selection of test systems.
Chapter 18  Quantitative relations: Observed responses and experimental variations.
Chapter 19  Exploring discrete variations: Near-orthogonal experiments by singular value.
Chapter 20  Optimisation when there are several response variables.
- w, I" Q! H, A$ L/ W) \5 ZChapter 21  A method for determining suitable order of introducing reagents in "one-pot" procedures.
Chapter 22  Books, journals, and computer programs.
Chapter 23  Concluding remarks.
Appendix A  Matrix calculus.
Appendix B  Statistical tables
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, {+ u4 i: ]0 p! B5 L+ Y[ 本帖最后由 fenglianxiang 于 2008-8-5 19:47 编辑 ]