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【分享】Ensuring the purity of platinum-cured silicone* |* y# E/ U! W6 r% ?+ n0 c
摘要：Platinum-cured silicone tubing plays a key role in manufacturing drugs and medicines in validated
' G* U/ @# z% C" ]1 Mand non-validated processes in the pharmaceutical/biopharmaceutical industry.+ p+ ^: _/ u; u" y
Though platinum-cured tubing is industry standard, platinum curing, in itself, does not guarantee8 I2 R$ r; W; H; u. B: t
a high level of tubing purity with low/safe levels of extractables. Watson-Marlow% o" P* Q0 a7 Q
achieves ultimate purity by driving off cytotoxic extractables through post-curing, a process
4 X* I* k# F' r y% Pstep many tubing manufacturers ignore. Some producers believe post-curing is not necessary,
% _, G5 w2 Q1 I# [( J) Aclaiming that the naturally lower extractables of platinum-cured tubing (compared with
7 q4 S5 ]* f/ y$ Nperoxide-cured silicone) is sufficient. This bulletin outlines the importance of post-curing for2 B+ g+ K+ l0 _: X' ^9 k1 s
the high-purity pharmaceutical/biopharmaceutical market, describing the key effects on the) k2 o: B; Y, R. r
tubing and the key benefits for the user. |
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发表于 2010-9-3 08:12:39
